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Table 1 Comparison of MST among different groups in three xenograft mouse models

From: Antitumor efficacy of D2C7-(scdsFv)-PE38KDEL, a novel immunotoxin targeting EGFRwt and EGFRvIII, by convection-enhanced delivery in orthotopic brain tumor mouse models

(Day) Vehicle P588 D2C7 Log-rank test
43 MST 14 15 43.5* 0.0010
NR6M MST 25 25 32 0.0074
D270MG MST 26 19.5 64** 0.0061
  1. *Last 4 mice were euthanized on Day 90;
  2. **Last 8 mice were euthanized on Day 64.