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Fig. 3 (abstract P166). | Journal for ImmunoTherapy of Cancer

Fig. 3 (abstract P166).

From: 32nd Annual Meeting and Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2017): Part One

Fig. 3 (abstract P166).

Characterization of the functional avidity of TCR in recognition of HLA-A2-peptide complex and alanine scanning for safety of TCR use. A. T2 cells loaded with or without H3.3K27M peptide, H3.3WT peptide or irrelevant HLA-A2 binding flu peptide (10 μg/ml) were co-cultured with either control or TCR-transduced Jurkat76CD8+ cells and Jurkat76CD8- cells in 1:1 ratio and assessed for IL-2 production by ELISA. Data represent three independent experiments with similar results. *p

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