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Table 2 Prediction performance for studied biomarkers

From: Predicting response to checkpoint inhibitors in melanoma beyond PD-L1 and mutational burden

Prediction Method Sensitivity Specificity PPV NPV Accuracy
Response Score (Training Dataset) 95.2% 74.1% 74.1% 95.2% 83.33%
Response Score (Test Dataset) 72.2% 81.8% 86.70% 64.30% 75.86%
Response Score (Combined) 84.6% 76.3% 78.60% 82.90% 80.52%
PD-L1 IHC (1% TPS) 34.2% 86.8% 72.20% 56.90% 60.53%
Mutational Burden 32.50% 78.90% 61.90% 52.60% 55.13%