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Fig. 5 | Journal for ImmunoTherapy of Cancer

Fig. 5

From: Local angiotensin II contributes to tumor resistance to checkpoint immunotherapy

Fig. 5

An abscopal effect on resistant tumors is induced by AGT silencing in local tumor combined with PD-1 blockage. a AGT-silenced 4T1 cells (AGT) and negative control (NC) were injected into single (unilateral) or two sides (bilateral) respectively of mammary fat pads in BALB/c mice. b 4T1 tumor-bearing mice were treated as indicated. The volume of each tumor was measured from each mouse (n=6) . Ns, no significance; **, P < 0.01

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