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Fig. 2 | Journal for ImmunoTherapy of Cancer

Fig. 2

From: A gene expression assay for simultaneous measurement of microsatellite instability and anti-tumor immune activity

Fig. 2

Gene expression signature of hypermutation status in TCGA dataset. Volcano plots show genes’ associations with hypermutation for colon adenocarcinoma (COAD), stomach adenocarcinoma (STAD), and uterine corpus endometrial carcinoma (UCEC). Genes with a false discovery rate (FDR) < 0.05 in COAD are colored orange and blue in all 3 panels based on the direction of their association with hypermutation in COAD. The genes used by the Hypermutation Predictor algorithm are highlighted in red (positive weights) and purple (negative weights)

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